RS09 是一种 LPS 肽模拟物，可作为一种候选 TLR4 激动剂佐剂。
货号:ajcx27300
CAS:1449566-36-2
分子式:C31H49N9O9
分子量：691.78
溶解度:H2O : 100 mg/mL (144.55 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.

Li et al (2016) Intranasal vaccination against HIV-1 with adenoviral vector-based nanocomplex using synthetic TLR-4 agonist peptide as adjuvant. Mol.Pharm. 13 885 PMID:26824411 |Shanmugam et al (2012) Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. PLoS One 7 e30839 PMID:22363498