NTRC 824 (Compound 5) 是一种有效的、选择性的神经降压素样非肽类神经降压素受体 2 (NTS2) 拮抗剂，IC50 为 38 nM，Ki 为 202 nM。
货号:ajcx27046
CAS:1623002-61-8
分子式:C25H26F3N3O6S
分子量：553.55
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Potent and selective non-peptide neurotensin (NTS) type-2 receptor antagonist (IC50 = 38 nM). Exhibits >150-fold selectivity for NTS2 over NTS1.

Thomas et al (2014) Identification of N-[(5-{[(4-methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-L-leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2. J.Med.Chem. 57 7472 PMID:25157640