An active metabolite of brinzolamide
货号:ajcx25388
CAS:N/A
分子式:C10H17N3O5S3·C2H2O4
分子量：445.5
溶解度:DMSO: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

N-desethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .¹It inhibits CAII and CAIV activities (IC₅₀s = 1.28 and 128 nM, respectively).

1.Kim, C.-Y., Whittington, D.A., Chang, J.S., et al.Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IVJ. Med. Chem.45(4)888-893(2002)