MB-07344 sodium 是一种有效的甲状腺激素受体 (TR)-β 激动剂，其结合亲和力 Ki 为 2.17 nM。MB-07344 与 Atorvastatin 合用在兔、狗和猴体内具有降胆固醇活性。
货号:ajcx16732
CAS:N/A
分子式:C19H25NaO5P
分子量：387.36
溶解度:DMSO: 300 mg/mL (774.47 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

MB-07344 sodium is a potent thyroid hormone receptor (TR)-β agonist with a Ki of 2.17 nM. MB-07344 sodium has additive cholesterol lowering activity in combination with Atorvastatin in rabbits, dogs and monkeys[1].

[1]. Ito BR, et al. Thyroid hormone beta receptor activation has additive cholesterol lowering activity in combination with atorvastatin in rabbits, dogs and monkeys. Br J Pharmacol. 2009 Feb;156(3):454-65.