PF-06380101 D8 (Aur0101 D8) 是 PF-06380101 的氘代物。PF-06380101 是一种 Auristatin 微管抑制剂,是一种细胞毒性 Dolastatin 10 类似物。
货号:ajcx36270
CAS:N/A
分子式:C39H54D8N6O6S
分子量:751.06
溶解度:DMSO : 35 mg/mL (46.60 mM; ultrasonic and warming and heat to 60°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
PF-06380101 D8 (Aur0101 D8) is a deuterium labeled PF-06380101. PF-06380101, an Auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue[1].
[1]. Maderna A, et al. Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications. J Med Chem. 2014 Dec 26;57(24):10527-43.