Mal-VC-PAB-DM1 是抗体偶联药物的一部分,由微管破坏剂 DM1 和 ADC linker Mal-VC-PAB 连接而成。
货号:ajcx35584
CAS:1464051-44-2
分子式:C61H82ClN9O17
分子量:1248.81
溶解度:DMSO : 75 mg/mL (60.06 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Mal-VC-PAB-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB [1].
[1]. Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.