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Pomalidomide 4'-PEG3-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pomalidomide 4'-PEG3-acid图片
包装:25mg
规格:98%
市场价:1603元
分子量:477.46

产品介绍
Cereblon ligand with PEG linker and terminal acid for onward chemistry
货号:ajcx27766
CAS:2138440-82-9
分子式:C22H27N3O9
分子量:477.46
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Pomalidomide - linker 2 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.


Remillard et al (2017) Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 56 5738 PMID:28418626