GSK 2250665A (Compound 13) 是一种选择性 Itk 抑制剂，pKi 为 9.2。
货号:ajcx27030
CAS:1246030-96-5
分子式:C26H29N5OS
分子量：459.61
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Itk inhibitor (pKi = 9.2). Exhibits selectivity for Itk over Aurora B kinase and Btk (pIC50 values are 6.4 and 6.5, respectively) and a panel of other kinases. Inhibits IFNγ production in PBMCs.

Alder et al (2013) Identification of a novel and selective series of Itk inhibitors via a template-hopping strategy. ACS Med.Chem.Lett. 12 948 PMID:24900590