规格: | 98% |
分子量: | 614.8 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Background:
PAR2 (1-6) amide (human) (scrambled) is a synthetic peptide that corresponds to residues 1-6 of the amino terminal tethered ligand of human PAR2 sequence with the amino acids at positions 1 and 2 reversed. It has been used as a negative control for the proteinase-activated receptor 2 (PAR2) agonist PAR2 (1-6) (human) in various cellular assays.1,2
参考文献
1. Miyata, S., Koshikawa, N., Yasumitsi, H., et al. Trypsin stimulates integrin a5b1-dependent adhesion to fibronectin and proliferation of human gastric carcinoma cells through activation of proteinase-activated receptor-2. J. Biol. Chem. 275(7), 4592-4598 (2000).
2. Miike, S., McWilliam, A.S., and Kita, H. Trypsin induces activation and inflammatory mediator release from human eosinophils through protease-activated receptor-2. J. Immunol. 167(11), 6615-6622 (2001).