PAR4 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) and an amide form of PAR4 (1-6) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence.
货号:ajcx17504
CAS:N/A
分子式:C33H46N8O7 • XCF3COOH
分子量：666.8
溶解度:Water: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PAR4 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) and an amide form of PAR4 (1-6) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence. It induces aggregation of rat platelets with an EC50 value of 40 μM. PAR4 (1-6) amide (100 μM) induces smooth muscle relaxation and prostaglandin E2 release in isolated mouse tracheal segments, effects that are inhibited by indomethacin .