Vc-seco-DUBA (SYD985) 是抗体偶联药物的一部分,由 DNA 烷化剂 DNA alkylator 和 ADC linker Vc-seco 连接而成。
货号:ajcx35522
CAS:1345681-58-4
分子式:C65H75ClN12O17
分子量:1331.81
溶解度:DMSO : 146.67 mg/mL (110.13 mM; ultrasonic and warming and heat to 60°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Vc-seco-DUBA (SYD985) is a drug-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco[1].
[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.