Fipronil 是一种杀虫剂，可作为昆虫 GABA 受体的选择性拮抗剂（蟑螂和大鼠受体的 IC50s = 30 nM 和 1,600 nM）。
货号:ajcx29346
CAS:120068-37-3
分子式:C12H4Cl2F6N4OS
分子量：437.15
溶解度:DMSO: 250 mg/mL (571.89 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC500s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.