NLRP3 inflammasome inhibitor
货号:ajcx27896
CAS:2068818-02-8
分子式:C18H16BCl3N2O2
分子量：409.5
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

NLRP3 inflammasome inhibitor (IC50 = 574 nM). Inhibits nigericin-induced inflammasome activation in THP-1 cells and Imiquimod induced IL-1β release from LPS-primed bone marrow-derived macrophages (BMDMs).

Baldwin et al (2017) Boron-based inhibitors of the NLRP3 inflammasome. Cell Chem.Biol. 24 1321 PMID:28943355