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S 07662
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
S 07662图片
规格:98%
分子量:300.38
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Constitutive androstane receptor (CAR) inverse agonist
货号:ajcx26958
CAS:883226-64-0
分子式:C16H16N2O2S
分子量:300.38
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Inverse agonist of the constitutive androstane receptor (CAR). Inhibits CAR activity via recruitment of nuclear receptor co-repressor (NCoR). Suppresses CITCO-induced CYP2B6 gene expression in human primary hepatocytes.


Küblbeck et al (2011) New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists. Mol.Pharm. 8 2424 PMID:22044162