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10-acetyl Docetaxel
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
10-acetyl Docetaxel图片
规格:98%
分子量:849.9
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
A derivative of paclitaxel and an inhibitor of microtubule depolymerization
货号:ajcx26400
CAS:125354-16-7
分子式:C45H55NO15
分子量:849.9
溶解度:DMF: 2 mg/ml,DMSO: 3 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): insol
纯度:98%
存储:Store at -20°C
库存:现货

Background:


10-acetyl Docetaxel is a derivative of paclitaxel and an inhibitor of microtubule depolymerization.1It inhibits calcium-induced depolymerization of calf brain microtubule protein (MTP) in a cell-free assay when used at 20 µM. 10-acetyl Docetaxel is cytotoxic to J774.2 cells (EC50= 0.05 µM).


1.Swindell, C.S., Heerding, J.M., Krauss, N.E., et al.Characterization of the taxol structure-activity profile for the locus of the A-ring side chainBioorg. Med. Chem. Lett.4(12)1531-1536(1994)