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L-Glutamine-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Glutamine-d5图片
规格:98%
分子量:151.2
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
An internal standard for the quantification of L-glutamine
货号:ajcx25710
CAS:14341-78-7
分子式:C5H5D5N2O3
分子量:151.2
溶解度:Water: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

L-Glutamine-d5is intended for use as an internal standard for the quantification of L-glutamine by GC- or LC-MS. L-Glutamine is a non-essential amino acid involved in many biochemical processes. It is synthesizedin vivoby glutamate and ammonia.1It serves as a substrate for glutamine synthetase in neurons for the biosynthesis of the major excitatory and inhibitory neurotransmitters glutamate and GABA.2L-Glutamine decreases adhesion of sickle red blood cells (RBCs) to human umbilical vein endothelial cells (HUVECs) when incubatedex vivowith patient-derived autologous plasma either alone or with LPS.3It has commonly been used in cell culture media. Formulations containing L-glutamine have been used in the treatment of sickle cell disease.


1.Eisenberg, D., Gill, H.S., Pfluegl, G.M.U., et al.Structure-function relationships of glutamine synthetasesBiochim Biophys. Acta.1477(1-2)122-145(2000) 2.Bak, L.K., Schousboe, A., and Waagepetersen, H.S.The glutamate/GABA-glutamine cycle: Aspects of transport, neurotransmitter homeostasis and ammonia transferJ. Neurochem.98(3)641-653(2006) 3.Niihara, Y., Matsui, N.M., Shen, Y.M., et al.L-glutamine therapy reduces endothelial adhesion of sickle red blood cells to human umbilical vein endothelial cellsBMC Blood Disord.5(4)(2005)