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16α-hydroxy Dehydroepiandrosterone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
16α-hydroxy Dehydroepiandrosterone图片
规格:98%
分子量:304.4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
A metabolite of dehydroepiandrosterone
货号:ajcx25298
CAS:1232-73-1
分子式:C19H28O3
分子量:304.4
溶解度:Chloroform: 10mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone .116α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosteronevia16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol .2


1.Miller, K.K.M., Cai, J., Ripp, S.L., et al.Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450Drug. Metab. Dispos.32(3)305-313(2004) 2.Hampl, R., and Starka, L.Minireview: 16α-Hydroxylated metabolites of dehydroepiandrosterone and their biological significanceEndocr. Regul.34(3)161-163(2000)