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Glycohyocholic Acid-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Glycohyocholic Acid-d4图片
包装:1mg
规格:98%
市场价:2963元
分子量:469.7

产品介绍
An internal standard for the quantification of glycohyocholic acid
货号:ajcx24994
CAS:N/A
分子式:C26H39D4NO6
分子量:469.7
溶解度:DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Glycohyocholic Acid-d4(GHCA-d4) is intended for use as an internal standard for the quantification of GHCA by GC- or LC-MS. GHCA is a glycine-conjugated form of the primary bile acid hyocholic acid .1GHCA is upregulated 6.6-fold in the serum of patients with cirrhosis induced by hepatitis C virus (HCV) compared to healthy controls.2Plasma levels of GHCA increase in patients who are no longer diabetic following gastric bypass surgery.3


1.Guo, L., Milburn, M.V., Ryals, J.A., et al.Plasma metabolomic profiles enhance precision medicine for volunteers of normal healthProc. Nat. Acad. Sci. USA112(35)E4901-E4910(2015) 2.Fitian, A.I., Nelson, D.R., Liu, C., et al.Integrated metabolomic profiling of hepatocellular carcinoma in hepatitis C cirrhosis through GC/MS and UPLC/MS-MSLiver Int.34(9)1428-1444(2014) 3.Yu, H., Ni, Y., Bao, Y., et al.Chenodeoxycholic acid as a potential prognostic marker for Roux-en-Y gastric bypass in Chinese obese patientsJ. Clin. Endocrinol. Metab.100(11)4222-4230(2015)