PS315 is an allosteric atypical protein kinase C (aPKC) inhibitor that acts by binding to the PIF-pocket. References: Zhang H, Neimanis S, Lopez-Garcia LA, Arencibia JM, Amon S, Stroba A, Zeuzem S, Proschak E, Stark H, Bauer AF, Busschots K, Jorgensen TJ, Engel M, Schulze JO, Biondi RM. Molecular mechanism of regulation of the atypical protein kinase C by N-terminal domains and an allosteric small compound. Chem Biol. 2014 Jun 19;21(6):754-65. doi: 10.1016/j.chembiol.2014.04.007. Epub 2014 May 15. PubMed PMID: 24836908.
纯度:≥98%
CAS:1221964-50-6