Fmoc-Gly-Gly-Phe-OtBu 是一种常用的可降解的抗体-药物偶联物 (ADCs) 的连接桥。
货号:ajcx15612
CAS:236426-37-2
分子式:C32H35N3O6
分子量:557.64
溶解度:DMSO: 200 mg/mL (358.65 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Fmoc-Gly-Gly-Phe-OtBu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[1]. Bak A, et al. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker. J Pept Res. 1999 Apr;53(4):393-402.