VH032-PEG3-acetylene 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 VH032 的 VHL 配体和 1 个 linker。
货号:ajcx15524
CAS:2098799-80-3
分子式:C31H42N4O7S
分子量:614.75
溶解度:DMSO: 50 mg/mL (81.33 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
VH032-PEG3-acetylene is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology[1].
[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.