SPP-DM1 是抗体-药物偶联物的一部分,由微管破坏剂 DM1 和 ADC linker SPP 连接而成。
货号:ajcx14844
CAS:452072-20-7
分子式:C44H59ClN4O14S2
分子量:967.54
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
SPP-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP[1].
[1]. Manu Lopus et al. Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules.