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R-BC154
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
R-BC154图片
包装:1mg
规格:98%
市场价:5921元
分子量:1212.37

产品介绍
High affinity fluorescent a4 beta 1/a9 beta 1 inhibitor; mobilizes HSCs
货号:ajcx27352
CAS:N/A
分子式:C55H61N9O13S3.CH3CO2H
分子量:1212.37
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

High affinity fluorescent α4β1/α9β1 inhibitor (Kd values are 12.7 and 38 nM, respectively); fluorescent version of BOP (Cat.No. 6047). Rapidly and preferentially mobilizes HSCs and progenitors in vivo. Excitation maximum, 561 nm; emissiosn maximum, 585 nm.


Cao et al (2014) Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vi Org.Biomol.Chem. 12 965 PMID:24363056 |Cao et al (2016) Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist. Nat.Commun. 7 11007 PMID:26975966