规格: | 98% |
分子量: | 274.3 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Background:
Sulfamethizole-d4is intended for use as an internal standard for the quantification of sulfamethizole by GC- or LC-MS. Sulfamethizole is a broad-spectrum sulfonamide antibiotic (MIC90s = 1.25-5,000 µg/ml against clinical isolates ofE. coliandK. pneumoniae).1It inhibits dihydropteroate synthase, an enzyme involved in folate biosynthesis. Formulations containing sulfamethizole have previously been used to treat urinary tract infections.
1.Wambaugh, M.A., Shakya, V.P.S., Lewis, A.J., et al.High-throughput identification and rational design of synergistic small-molecule pairs for combating and bypassing antibiotic resistancePLoS Biol.15(6):e2001644(2017)