规格: | 98% |
分子量: | 114.1 |
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
Background:
D-Ornithine lactam is a building block.1,2It has been used in the synthesis of hepatitis C virus (HCV) non-structural protein 5B (NS5B) inhibitors, as well as αVβ3 integrin receptor antagonists.
1.Li, P., Dorsch, W., Lauffer, D.J., et al.Discovery of novel allosteric HCV NS5B inhibitors. 2. Lactam-containing thiophene carboxylatesACS Med. Chem. Lett.8(2)251-255(2017) 2.Kubota, D., Ishikawa, M., Ishikawa, M., et al.Tricyclic pharmacophore-based molecules as novel integrin ɑvβ3 antagonists. Part IV: Preliminary control of ɑvβ3 selectivity by meta-oriented substitutionBioorg. Med. Chem.14(12)4158-4181(2006)