| CAS NO: | 477-90-7 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1g | 电议 |
| 5g | 电议 |
| Molecular Weight (MW) | 328.27 |
|---|---|
| Formula | C14H16O9 |
| CAS No. | 477-90-7 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: > 10 mM |
| Water: NA | |
| Ethanol: NA | |
| Other info | Chemical Name: (2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3, 4,4a,10b-tetrahydro-2H-pyrano[3,2-c]isochromen-6-one InChi Key: YWJXCIXBAKGUKZ-HJJNZUOJSA-N InChi Code: InChI=1S/C14H16O9/c1-21-11-5(16)2-4-7(9(11)18)12-13(23-14(4)20)10(19)8(17)6(3-15)22-12/h2,6,8,10,12-13,15-19H,3H2,1H3/t6-,8-,10+,12+,13-/m1/s1 SMILES Code: O=C1C2=C(C(O)=C(OC)C(O)=C2)[C@@]3([H])[C@]([C@@H](O)[C@H](O)[C@@H](CO)O3)([H])O |
| Synonyms | Cuscutin |
| In Vitro | In vitro activity: The naloxone-precipitated withdrawal symptom (jumping frequency) was significantly ameliorated (50% of control group) by administration of bergenin (20 mg/kg) in morphine-treated mice. Furthermore, morphine-induced down-regulation of glutathione (GSH) contents was reversed by bergenin administration in the frontal cortex and liver. |
|---|---|
| In Vivo | Bergenin attenuated inflammatory cell infiltration and decreased the concentration of NO, TNF-α, IL-1β, and IL-6, which were increased in LPS-induced mouse mastitis. |
| Animal model | Mouse |
| Formulation & Dosage | |
| References | Inflammation. 2015;38(3):1142-50; Arch Pharm Res. 2015 Jun;38(6):1248-54. |
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