Succinyladenosine，是胞内腺苷酸(S-AMP)经5-核苷酸酶脱磷酸化的产物，是腺苷酸琥珀酸酶(ASL)缺乏的生化标志。
货号:ajcx32112
CAS:4542-23-8
分子式:C14H17N5O8
分子量：383.31
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Succinyladenosine, the metabolic product of dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase, is a biochemical marker of adenylosuccinase (ASL) deficiency[1].

The presence of high concentrations of Succinyladenosine (S-Ado) in the human cerebrospinal fluid (CSF) in the range of 100-500 μmol/L is a diagnostic marker for inherited enzyme deficiency of ASL[1].

[1]. J Krijt, et al. Identification and Determination of Succinyladenosine in Human Cerebrospinal Fluid . J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):53-8.