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&gamma-1-Melanocyte Stimulating Hormone(MSH),amide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
规格:98%
分子量:1512.9
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
γ-1-MelanocyteStimulatingHormone(MSH),amide是一种含11个氨基酸的多肽。γ-1-MelanocyteStimulatingHormone通过激活黑皮质素受体3(MC3-R)来调节钠(Na+)平衡和血压。
货号:ajcx31822
CAS:N/A
分子式:C72H97N21O14S
分子量:1512.9
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

γ-1-Melanocyte Stimulating Hormone (MSH), amide is a 11-amino acid peptide. γ-1-Melanocyte Stimulating Hormone (MSH) regulates sodium (Na+) balance and blood pressure through activation of the melanocortin receptor 3 (MC3-R).

γ-Melanocyte Stimulating Hormone (γ-MSH) regulates a multitude of metabolic functions including energy homeostasis, food intake, sodium (Na+) balance, and blood pressure regulation. γ-MSH is processed from the precursor hormone pro-opio-melanocortin (POMC) in the pituitary gland, where component peptides are released into the cerebral spinal fluid and systemic circulation. The natural receptor for γ-MSH is the melanocortin receptor 3 (MC3-R), a G-protein-coupled receptor that activates adenylate cyclase and is expressed in brain (hypothalamus, cortex, and thalamus), gut, placenta, and kidney. γ-MSH regulates Na+ balance by inducing urinary Na+ excretion (natriuresis) under conditions of high dietary salt intake[1].


[1]. Kathpalia PP, et al. The natriuretic mechanism of Gamma-Melanocyte-Stimulating Hormone. Peptides. 2011 May;32(5):1068-72.