Medronic acid (Methylenediphosphonic acid) 是亚甲基取代的二膦酸盐。 Medronic acid 对骨基质中的羟基磷灰石晶体的表面具有亲和力并且粘附在其上。Medronic acid 在类骨质矿化的位点累积并且可以在骨成像中与放射性同位素复合使用。
货号:ajcx38690
CAS:1984-15-2
分子式:CH6O6P2
分子量：176
溶解度:DMSO : 250 mg/mL (1420.45 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. Medronic acid accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes in bone imaging.

[1]. Ohta Y, et al. Salt Tolerance Enhancement of Liquid Chromatography-Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Using Matrix Additive MethylenediphosphonicAcid. Mass Spectrom (Tokyo). 2014;3(1):A0031.