(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate 是一种有效的 CDK2,JAK2 和 FLT3 抑制剂,用于癌症研究。
货号:ajcx37596
CAS:N/A
分子式:C29H32N4O8
分子量:564.59
溶解度:DMSO : 250 mg/mL (442.80 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(E/Z)-Zotiraciclib citrate is a potent CDK2, JAK2, and FLT3 inhibitor[1].
[1]. William AD, et al. Discovery of kinase spectrum selective macrocycle (16E)-14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a potent inhibitor of cyclin dependent kinases (CDKs), Janus kinase 2 (JAK2), and fms-like tyrosine kinase-3 (FLT3) for the treatment of cancer. J Med Chem. 2012;55(1):169-196.