PV-1115 is a potent and highly selective Chk2 inhibitor. References: Lountos GT, Jobson AG, Tropea JE, Self CR, Zhang G, Pommier Y, Shoemaker RH, Waugh DS. Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy. J Struct Biol. 2011 Dec;176(3):292-301. doi: 10.1016/j.jsb.2011.09.008. Epub 2011 Sep 22. PubMed PMID: 21963792; PubMed Central PMCID: PMC3210331.
纯度:≥98%
CAS:1093793-10-2