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X77
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
X77图片
规格:98%
分子量:459.58
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
X77 是 SARS-CoV-2 蛋白酶 (SARS-CoV-2 Mpro) 的有效非共价键抑制剂。X77 与 SARS-CoV-2 Mpro结合的 Kd 值为 0.057 μM。
货号:ajcx33868
CAS:2455518-33-7
分子式:C27H33N5O2
分子量:459.58
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

X77 is a potent non-covalent inhibitor of the main protease of SARS-CoV-2 (SARS-CoV-2 Mpro)[1]. X77 binds to SARS-CoV-2 Mpro with a Kd value of 0.057 μM[2].

X77 can bind to SARS-CoV-2 Mpro (PDB code: 6W63). SARS-CoV-2 Mpro (PDB code: 6W63) is the main protease of SARS-CoV-2 and is one of the most important drug targets among coronaviruses[1].

[1]. Sohini Chakraborti, et al. Drug Repurposing Approach Targeted Against Main Protease of SARS-CoV-2 Exploiting ’Neighbourhood Behaviour’ in 3D Protein Structural Space and 2D Chemical Space of Small Molecules.
[2]. Alexander M Andrianov, et al. Computational discovery of small drug-like compounds as potential inhibitors of SARS-CoV-2 main protease. J Biomol Struct Dyn