A Certified Reference Material
货号:ajcx24578
CAS:1184983-42-3
分子式:C20H18D3N•HCl
分子量：314.9
溶解度:
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Cyclobenzaprine-d₃(hydrochloride) (CRM) contains three deuterium atoms at the terminal methyl group. It is intended for use as an internal standard for the quantification of cyclobenzaprine by GC- or LC-mass spectrometry. Cyclobenzaprine is a skeletal muscle relaxant that also has sedative properties.^1,2,3It has been shown to antagonize muscarinic receptors (K_is = 25, 60, and 6 nM for M₁, M₂, and M₃, respectively), serotonin 5-HT₂receptors (K_is = 56 and 330 nM for 5-HT_2Cand 5-HT_2B, respectively), and histamine H₁receptor (IC₅₀= 20 nM).^4,5,6

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