| 包装: | 1mg |
| 规格: | 98% |
| 市场价: | 3333元 |
| 分子量: | 221.3 |
Background:
N,O-Diacetyltyramine is a fungal metabolite that has been found inP. endophyticaand has diverse biological activities.1It is active against a panel of 13 bacteria (MICs = 8-128 µg/ml), as well as a panel of nine fungi (MICs = 64-256 µg/ml). N,O-Diacetyltyramine is cytotoxic to MDA-MB-231, HeLa, MCF-7, and OAW42 cancer cells when used at concentrations ranging from 10 to 5,000 nM. It is larvicidal againstA. aegypti,A. albimanus, andC. quinquefasciatusmosquitos (LC50s = 724.8, 403.1, and 506.7 ppm, respectively).2
1.Mangamuri, U.K., Vijayalakshimi, M., Poda, S., et al.Bioactive metabolites produced by pseudonocardia endophytica VUK-10 from mangrove sediments: Isolation, chemical structure determination and bioactivityJ. Microbiol. Biotechnol.25(5)629-636(2015) 2.Quevedo, R., Nunez-Dallos, N., and Quinones, M.L.Larvicidal activity of single and macrocyclic tyrosine derivatives against three important vector mosquitoesRes. Chem. Intermed.41(8)5283-5292(2014)
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