CAS NO: | 74248-92-3 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
LY-79771 is a phenethanolamine antiobesity agent. LY79771 can be effective in preventing fat regain following energy deprivation. References: Blin N, Nahmias C, Drumare MF, Strosberg AD. Mediation of most atypical effects by species homologues of the beta 3-adrenoceptor. Br J Pharmacol. 1994 Jul;112(3):911-9. PubMed PMID: 7921620; PubMed Central PMCID: PMC1910199. 2: Blin N, Camoin L, Maigret B, Strosberg AD. Structural and conformational features determining selective signal transduction in the beta 3-adrenergic receptor. Mol Pharmacol. 1993 Dec;44(6):1094-104. PubMed PMID: 7903415. 3: Parente JA Jr, Berdanier CD. Drugs that suppress hepatic fat synthesis in starved-refed BHE/cdb rats also have an effect on muscle protein synthesis. Proc Soc Exp Biol Med. 1993 Nov;204(2):172-9. PubMed PMID: 8415772. 4: Cooper DA, Berdanier CD. The drug LY79771 affects fat regain by starved and refed BHE rats. J Nutr. 1991 Nov;121(11):1827-33. PubMed PMID: 1941191. 5: Ashwell M, Stirling D, Freeman S, Holloway BR. Immunological, histological and biochemical assessment of brown adipose tissue activity in neonatal, control and beta-stimulant-treated adult dogs. Int J Obes. 1987;11(4):357-65. PubMed PMID: 2889691. 6: Holloway BR, Stribling D, Freeman S, Jamieson L. The thermogenic role of adipose tissue in the dog. Int J Obes. 1985;9(6):423-32. PubMed PMID: 3007382. 7: Yen TT. The antiobesity and metabolic activities of LY79771 in obese and normal mice. Int J Obes. 1984;8(1):69-78. PubMed PMID: 6368435. 8: Yen TT, McKee MM, Stamm NB, Bemis KG. Stimulation of cyclic AMP and lipolysis in adipose tissue of normal and obese Avy/a mice by LY79771, a phenethanolamine, and stereoisomers. Life Sci. 1983 Mar 28;32(13):1515-22. PubMed PMID: 6300583. 9: Shaw WN, Schmiegel KK, Yen TT, Toomey RE, Meyers DB, Mills J. LY7977 a novel compound for weight control. Life Sci. 1981 Nov 16;29(20):2091-101. PubMed PMID: 7053089.
纯度:≥98%
CAS:74248-92-3