| CAS NO: | 520-26-3 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 1g | 电议 |
| 2g | 电议 |
| 5g | 电议 |
| 10g | 电议 |
| 50g | 电议 |
| 100g | 电议 |
| 500g | 电议 |
| Molecular Weight (MW) | 610.56 |
|---|---|
| Formula | C28H34O15 |
| CAS No. | 520-26-3 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 122 mg/mL (199.81 mM) |
| Water: <1 mg/mL | |
| Ethanol: <1 mg/mL | |
| Other info | Chemical Name: (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one InChi Key: QUQPHWDTPGMPEX-QJBIFVCTSA-N InChi Code: InChI=1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1 SMILES Code: O=C1C[C@@H](C2=CC=C(OC)C(O)=C2)OC3=C1C(O)=CC(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)=C3 |
| Synonyms | Cirantin; Hesperetin 7-rutinoside; HP |
| In Vitro | In vitro activity: hesperidin and linarin are two of the main constituent of Valeriana's extract exhibiting a high affinity to KATP channel, which are related to the control of Ca++ concentration and release of GABA in synaptic nerve terminal, mainly on cells of SN. |
|---|---|
| In Vivo | Hesperidin was dissolved in 1% carboxymethyl cellulose (CMC) and administered orally at a dose of 50 mg/kg for 10 consecutive days. In the control group, rats were treated with the corn oil and 1% CMC vehicle. |
| Animal model | Rats |
| Formulation & Dosage | Dissolved in 1% carboxymethyl cellulose (CMC) and administered orally at a dose of 50 mg/kg |
| References | BMC Cancer. 2015 Oct 12;15:682; Arch Med Sci. 2016 Jun 1;12(3):486-93. |
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