A vitamin K analog
货号:ajcx21208
CAS:1607447-79-9
分子式:C15H17NO2
分子量：243.3
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 20 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.¹It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED₅₀s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED₅₀s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively).

1.Li, X., Himes, R.A., Prosser, L.C., et al.Discovery of the first vitamin K analogue as a potential treatment of pharmacoresistant seizuresJ. Med. Chem.63(11)5865-5878(2020)