YVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO.
货号:ajcx19064
CAS:N/A
分子式:C21H30N4O7•XCF3COOH
分子量：450.5
溶解度:Water: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

YVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO . It prevents ICE-like and CPP32-like proteinase activity and inhibits apoptosis induced by ceramide or irinotecan in 4B1 cells when used at a concentration of 600 µM. YVAD-CHO (100 µM) also prevents chromogranin A-induced cell death of primary rat microglia but not primary rat cerebellar granule neurons.