SARS-CoV-2-IN-6 是一种 SARS-CoV-2 3CLpro 抑制剂,显示了有效的酶抑制活性,IC50 值 73 nM。
货号:ajcx36794
CAS:N/A
分子式:C17H13ClN2O2
分子量:312.75
溶解度:DMSO : 100 mg/mL (319.74 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
SARS-CoV-2-IN-6 is a SARS-CoV-2 3CLpro inhibitor that shows the most potent enzyme inhibitory IC50 value of 73 nM.
[1]. Ghosh AK, et al. Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. J Med Chem. 2021 Oct 14;64(19):14702-14714.