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BMVC2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BMVC2图片
规格:98%
分子量:657.33
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
BMVC2 (o-BMVC) 是 BMVC 的双取代咔唑衍生物,是一种 G 四联体 (G4) 稳定剂。
货号:ajcx36732
CAS:850559-51-2
分子式:C28H25I2N3
分子量:657.33
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

BMVC2 (o-BMVC) is a bisubstitute carbazole derivative of BMVC. BMVC2 is a G-quadruplex (G4) stabilizer[1].

BMVC2 by monitoring the disappearance of the 291 nm CD signals of d[AG3(T2AG3)3] (HT22) after adding Cu2+ is screened, a longer unfolding time would dictate a better G4 stabilizer. The unfolding curve of HT22 in the presence of BMVC2 can be fitted by using two time constants of 133.7 s (29%) and 2816 s (71%), which are similar to the unfolding parameters of BMVC[1].

[1]. Jen-Fei Chu, et al. A Novel Method for Screening G-quadruplex Stabilizers to Human Telomeres. Journal of the Chinese Chemical Society, 2011, 58, 296-300.