AM-Imidazole-PA-Boc 是一种 PROTAC linker，属于 alkyl chain 类。AM-Imidazole-PA-Boc 可用于合成 PROTAC IRAK4 degrader-1 。
货号:ajcx36604
CAS:2357108-99-5
分子式:C12H22N4O2
分子量：254.33
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

AM-Imidazole-PA-Boc is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC IRAK4 degrader-1 [1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.