您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > SPDP-C6-NHS ester
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
SPDP-C6-NHS ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SPDP-C6-NHS ester图片
规格:98%
分子量:425.52
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
SPDP-C6-NHSester是一种PROTAClinker,属于alkyl/ether类。可用于合成PROTAC分子。
货号:ajcx32036
CAS:158913-22-5
分子式:C18H23N3O5S2
分子量:425.52
溶解度:DMSO: 100 mg/mL (235.01 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562