Lenalidomide-acetylene-C5-COOH(compound43;Cereblonligand-linkerConjugate)是一种基于Lenalidomide的，可募集CRBN蛋白的Cereblon配体。可通过linker与靶蛋白配体连接，形成PROTAC分子。
货号:ajcx30904
CAS:2429878-72-6
分子式:C21H22N2O5
分子量：382.41
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-acetylene-C5-COOH can be connected to the ligand for protein by a linker to form PROTAC[1].

[1]. Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.