FlavokawainA是一种抗癌试剂(anticarcinogenicagent)，是kava提取物中的查耳酮，具有抗肿瘤活性。FlavokawainA通过Bax蛋白依赖和线粒体依赖的凋亡途径诱导细胞凋亡(apoptosis)。FlavokawainA有潜力用于膀胱癌的相关研究。
货号:ajcx30660
CAS:3420-72-2
分子式:C18H18O5
分子量：314.33
溶解度:DMSO: 100 mg/mL (318.14 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1].

[1]. Xiaolin Zi, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.