Boc-NH-PEG5-CH2CH2COOH是一种基于PEG的PROTAClinker，用于合成PROTAC。
货号:ajcx30304
CAS:1347750-78-0
分子式:C18H35NO9
分子量：409.47
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Boc-NH-PEG5-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Nathanael Gray, et al. Bifunctional compounds for her3 degradation and methods of use. WO2017117474A1.