TrkA-IN-1 是一种有效的选择性肌球蛋白相关激酶 A (TrkA) 抑制剂，在基于细胞的测定中，IC50 为 99 nM。TrkA-IN-1 具有镇痛作用。
货号:ajcx29750
CAS:1680179-43-4
分子式:C25H20N4O
分子量：392.45
溶解度:DMSO: 8.33 mg/mL (21.23 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

TrkA-IN-1 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 of 99 nM in a cell-based assay. TrkA-IN-1 has analgesic activity[1].

[1]. Su HP , et al. Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E297-E306.