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Pexiganan(acetate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pexiganan(acetate)图片
规格:98%
分子量:2477.2
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
An antimicrobial peptide
货号:ajcx28432
CAS:172820-23-4
分子式:C122H210N32O22 ? XC2H4O2
分子量:2477.2
溶解度:DMF: Slightly soluble,DMSO: Slightly soluble,Ethanol: 12 mg/ml,PBS (pH 7.2): 5 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Pexiganan is a synthetic antimicrobial peptide.1It is active against various clinical isolates of bacteria from patients with diabetic foot infections, includingS. aureus, methicillin-resistantS. aureus(MRSA), andP. aeruginosa(MICs = 16-32, 16-32, and 8-16 µg/ml, respectively). Pexiganan (1 mg/kg) decreases lethality in a mouse model of sepsis induced byA. baumannii.2

1.Flamm, R.K., Rhomberg, P.R., Simpson, K.M., et al.In vitro spectrum of pexiganan activity when tested against pathogens from diabetic foot infections and with selected resistance mechanismsAntimicrob. Agents Chemother.59(3)1751-1754(2015) 2.Cirioni, O., Simonetti, O., Pierpaoli, E., et al.Enhanced efficacy of combinations of pexiganan with colistin versus Acinetobacter Baumannii in experimental sepsisShock46(2)219-225(2016)