KIT inhibitor
货号:ajcx26814
CAS:1001083-74-4
分子式:C20H16FN3O2
分子量：349.36
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

KIT inhibitor; inhibits phosphorylation of KIT, STAT3, STAT5 and Akt. Suppresses proliferation of OCI/AML3 cells (IC50 = 175 nM). Caspase-dependant apoptosis inducer.

Faderl et al (2009) Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. Cancer Res. 69 3910 PMID:19383925