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Ac-VEID-AMC(ammonium acetate salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ac-VEID-AMC(ammonium acetate salt)图片
规格:98%
分子量:673.7
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
A caspase-6 fluorogenic substrate
货号:ajcx24936
CAS:N/A
分子式:C32H43N5O11·XC2H7NO2
分子量:673.7
溶解度:DMSO: 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis.1It has also been reported to be cleaved by related proteases, including caspase-8.2Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm.


1.Talanian, R.V., Quinlan, C., Trautz, S., et al.Substrate specificities of caspase family proteasesJ. Biol. Chem.272(15)9677-9682(1997) 2.Chae, H.J., Park, K.M., Lee, G.Y., et al.Je-Chun-Jun induced apoptosis of human cervical carcinoma HeLa cellsActa Pharmacologica Sinica25(10)1372-1379(2004)