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4'-Acetyl Chrysomycin A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4'-Acetyl Chrysomycin A图片
规格:98%
分子量:538.5
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
A bacterial metabolite with antibacterial and anticancer activities
货号:ajcx24042
CAS:N/A
分子式:C29H30O10
分子量:538.5
溶解度:
纯度:98%
存储:Store at -20°C
库存:现货

Background:

4'-Acetyl chrysomycin A is a bacterial metabolite and derivative of chrysomycin A that has been found inStreptomycesand has antibacterial and anticancer activities.1It is active against strains of methicillin-resistantS. aureus(MRSA) and vancomycin-resistant strains ofE. faecalisandE. faecium(MICs = 0.5-2 µg/ml for all). 4'-Acetyl chrysomycin A is cytotoxic against a panel of human cancer cell lines, including doxorubicin-sensitive or -resistant cells (IC50s = 0.085-0.26 and 3.4-16 ng/ml, respectively).


1.Wada, S.-I., Sawa, R., Iwanami, F., et al.Structures and biological activities of novel 4'-acetylated analogs of chrysomycins A and BJ. Antibiot. (Tokyo)70(11)1078-1082(2017)